This report details plans associated with the 2025 Regional Monitoring Program for Water Quality in San Francisco Bay (RMP) dry season water cruise. The RMP water sampling program was redesigned in 2002 to adopt a randomized sampling design at thirty-one stations in place of the twenty-six base program stations sampled previously. In 2007, the number of stations was decreased to twenty-two stations, and it remains as such for 2025. The analytes for 2025 are based on the revised Status and Trends design described in the report Foley et al. in review.