Toxicity Measure Definitions, Measure,Definition #survivors,Number of suviving individuals out of 20 % survival,Percent suvival Biomarker Measure Definitions (Results relate to relative concentration of heat shock proteins present), Measure,Definition hsp60,Heat Shock Protein 60 hsp70,Heat Shock Protein 70 hsp70-gill,Heat Shock Protein 70 - from Gill - Supernatant hsp70-mantle,Heat Shock Protein 70 - from Mantle - Supernatant hsp70-DG,Heat Shock Protein 70 - from Digestive Gland - Supernatant hsp76,Heat Shock Protein 76 "Histology Measure Definitions (Results are related to presence of lesions: none (0), mild (1), moderate (2), severe (3); n= not applicable)", Measure,Definition DINF,DINF = inflammation in digestive gland DMA,DMA = macrophage aggregates in digestive gland GCN,GCN = primary and secondary germ cell necrosis (primary and secondary spermatogonia and immature ova) GINF,GINF = inflammation in gonad GMA,GMA = macrophage aggregates in gonad SCN,SCN = supporting cell necrosis (auxillary or sertoli cells) TBN,TBN = Tubular cell necrosis TDA,TDA = tubular dilation or atrophy LMS,Lysosomal Membrane Stability (expressed as destabilization time in minutes)